The Greed of Big Pharma + Total Compliance Reformer Schools = More Child Doping

From Alternet, a clip from an excerpt of this book:

Prices of ADHD meds at the middle dose for ninety pills on Drugstore.com in 2011 were Concerta, $540; Vyvanse, $532; Intuniv, $500; Adderall, $278; and Ritalin, $191. The price of the most common antidepressants, like Prozac, Celexa, Lexapro, Zoloft, Cymbalta, and Wellbutrin, for ninety pills, was around $380. Two of the drugs prescribed to Rebecca Riley by Dr. Kifuji happen to be quite pricey. Drugstore.com rates in 2011 for 180 500 mg tablets of Seroquel were $1,048 and for Depakote, $708.

 

Among drug reps, it is common knowledge that kids are a lucrative market. At the urging of doctors, parents, and teachers, kids are required to buck up and take their meds. In the words of Gwen Olsen, who worked for fifteen years as a drug rep with such pharmaceuticalindustry mainstays as Johnson & Johnson and Bristol-Myers Squibb: “Children are known to be compliant patients and that makes them a highly desirable market for drugs, especially when it pertains to largeprofit-margin psychiatric drugs, which can be wrought with noncompliance because of their horrendous side-effect profiles.” Most large-profit-margin psychiatric drugs are approved by the FDA strictly for use with adults, not kids. However, doctors are allowed to use their discretion and prescribe them to kids for “offlabel” purposes. Doctors can use their medical instincts to determine whether a drug approved for adults might also ease the suffering of kids. But there is no scientific backing for such use. The studies haven’t been conducted. The FDA approval hasn’t been obtained. Off-label prescribing relies on doctors’ instincts alone. While drug manufacturers and their marketing staff are bound by law not to influence doctors’ off-label prescribing habits, it’s not the law that’s foremost on the minds of drug reps fanning out to doctors’ offices all over the country.

 

It’s upping sales. The right to use adult meds with kids for off-label purposes has left many physicians easy prey to drug reps and pharmaceutical companies’ marketing ploys. A glaring example of this was uncovered in the largest health-care fraud case ever handled by the US Department of Justice, in 2009.  Pfizer agreed to a $2.3 billion settlement for promoting off-label use of a variety of drugs, one of which was the antipsychotic medication Geodon. One of Pfizer’s illegal actions was paying 250 child psychiatrists to promote its off-label use with teens. Dr. Neil Kaye, for example, was paid $4,000 a day in speaker’s fees to give speeches to other physicians with titles like, “the off-label use of Geodon in Adolescents.” Geodon happens to be a highly expensive and highly profitable drug. At Drugstore.com in 2011, it cost $1,400 for 180 40 mg capsules. It currently nets Pfizer $1 billion a year.

New Cure for ADHD: Recess

From HuffPo:

On April 15, the Centers for Disease Control and Prevention held a media conference at the National Press Club in Washington, D.C., to announce the release of a new report on school-based physical activity and its association with academic performance.

The report -- a review of 50 studies published in 43 articles -- reached a conclusion that is no great surprise to those of us who know kids well (I have five), and work to promote their health (both physical, and intellectual). Physical activity is good for body and brain, alike. As often seems to be the case, modern analytic methods and systematic review of evidence landed us right in the middle of Grandma's common sense counsel: sound mind, sound body.

The fundamental findings of CDC's 129-page report were that diverse interventions for kids of various ages produced a net improvement in academic performance more often than not. Over 50 percent of the studies analyzed improved some measure of cognition or academics. An additional 48 percent of the interventions contributed to fitness and health without compromising academics.

The benefits of physical activity probably need no introduction. Being active, in combination with eating well, is both the first, and only truly reliable, line of defense against the clear and omnipresent danger of childhood obesity. Even when physical activity is not preventing overweight, it is promoting vitality and helping to prevent disease. Independent of weight control, exercise can help keep diabetes at bay.

But while fitness, vitality, the avoidance of disease and the pleasures and glories of athletics might make a totally persuasive argument for routine exercise, the benefits don't stop there. The mind and body are genuinely connected, and the soundness of one redounds to the other.

Just consider that rates of behavioral disorders in childhood -- attention deficit disorder in particular -- are at an all-time, unprecedented high. How do we account for that? Certainly, there has been no radical shift in the genes that oversee the construction of children in the last generation. Children are much the same as they ever were. Their typical day is as it never was before.

Children used to play outside. They used to have physical education and recess during the school day. More and more, we take naturally rambunctious children, send them to schools from which recess and Phys Ed have been all but banished, bolt them to chairs all day long, and then watch them grow into adults we can't get off couches with crowbars! And, alas, along the way we medicate more and more of them for attention disorders. Could it be that WE are the ones who have not been paying sufficient attention to the natural, healthy restlessness of children?

Some years ago, when my son, Gabriel, was five, he joined the rest of my family in attending an evening talk I gave at Dartmouth. Whereas my daughters, all older than Gabe, were able to sit attentively as my talk began, Gabe was fidgeting out of his seat and tormenting his poor mother within minutes.

The story that ensued -- one I have told many times -- is that I interrupted my talk to intervene on my wife's behalf. I asked Gabe to run a lap around the large auditorium in which I was speaking. He did, completed it, then popped up from his seat and took off for another. As he came around at the end of lap two and kept on going, three other kids took off after him. When the four of them came around and kept going, several dozen children joined in!

As the ruckus played out, I noted to my audience that what we were observing was more important than anything I might be saying. I presumed all of the kids running laps around us were healthy. My son, certainly, was healthy -- although, lord knows, if you were cooped up with him at that age for any length of time you'd be tempted to medicate either him or yourself! But he was, and is, healthy. Rambunctiousness in children is normal.

And it should be treated with recess, not Ritalin! Gabriel had shown me how.

The result of Gabe's fidgety disruption was a program called ABC for Fitness (Activity Bursts in the Classroom), ultimately crafted not only by my research staff, but by experts in physical education, notably Marvin Christley with the New Haven, CT, Public Schools, and experts in education from the CT Department of Education. The program, available to all for free at http://www.davidkatzmd.com/abcforfitness.aspx, not only allows for intermittent bursts of activity throughout the day whenever kids 'need' one, but matches aerobic routines to grade level and subject matter. Teaching time actually goes up!

The program has rapidly spread to thousands of schools, because it's so easy, costs nothing, and works so well. We've analyzed the results in over 1,000 children and found not only improvements in fitness, but stable academic performance, and significant declines in medication use for both asthma, and ADHD. This report has been accepted for publication, and will be out soon.

The traditional three 'R's -- reading, writing, and 'rithmetic- remain as important as ever. Our own work, CDC's review of 50 studies, and every parent's experience with children indicate there is a strong case to add back a fourth that contributes its own benefits, while supporting the time-honored three. It is variations on the theme of recess- not Ritalin!